By default, Hand2Note folder is located in C:/Program Files/Hand2Note. If this folder takes up too much space, most likely, most of the space is occupied by log files (logs folder).
You can completely delete this folder, if its size bothers you, it will not affect the operation of the software.
You can also disable logging in the program settings. To do this, go to Settings → Other options → Logging, uncheck all the options and click “Save”:
After that, Hand2Note will save only the most necessary system logs, which will not take up much space.
A substantial portion of the disk space may also be occupied by the database. You can move the database to another disk, or simply create a clean database and import only relevant hands into it.